Tricyclic Antidepressants » Clomipramine (Anafran) » dothiepin zolpidem

dothiepin zolpidem

Question:

> Have you used dothiepin before. 225 mcg is more than what is allowed. > I want to know how I can stop taking these drugs. Would I have > withdrawal symtoms? What are the side effects of dothiepin. I feel > like zombie.

I’ve taken dothiepin up to 225mg (not mcg!) which is the approved maximum, but the recommendation is that anything above 150mg should be taken under supervision, preferably as an inpatient (fortunately my GP trusted me to not exceed that dose and report any problems straight away) The side-effects tended to change over time; to start with, and at every subsequent dose increase, it tended to cause a lot of drowsiness, which was replaced after a couple of weeks by insomnia, anxiety and agitation (although that isn’t a particularly common effect AIUI) Other side-effects were the usual ones expected from TCAs, namely slight problems with dry mouth (very nasty overnight), slight constipation, and marginally slowed thinking.  Nothing much else to report, though… I stopped overnight from 225mg and didn’t notice any withdrawal problems.  That’s just me, though, I also didn’t have any problems stopping paroxetine suddenly from 50mg which a lot of people do find problematic. Chris.

Response:

- Hide quoted text — Show quoted text -> I am on 3 x75 mcg dothiepin and 1 x10 mcg zolpidem for depression. My > depression has resulted in not being able to sleep nearly 3 months. > The above medication is supposed to help me. I seem to be getting > worse. Has anybody used the above meidcaion. Will it work eventually? > I have been on this medicaiton now more than one month. Please help. > Hopefully it should work after a couple of weeks.  Most people find > dothiepin to be quite sedating, but is can have a more activating > effect in a few.  I’d give it about six weeks, to be honest, and > if there’s still no luck I’d move onto something else.  I found > both clomipramine and mirtazapine extremely sedating, considerably > moreso than dothiepin whose effect tended to wear off a couple of > weeks after each dose increase. > Chris.

Have you used dothiepin before. 225 mcg is more than what is allowed. I want to know how I can stop taking these drugs. Would I have withdrawal symtoms? What are the side effects of dothiepin. I feel like zombie. Emrom

Response:

Zolpidem is "Ambien", a sleeping pill.  It should help you sleep, at least for a few hours. Sorry I don’t know what "Dothiepin" is.

Response:

> I am on 3 75 mcg dothiepin and 1 10 mcg zolpidem for depression. My > depression has resulted in not being able to sleep nearly 3 months. > The above medication is supposed to help me. I seem to be getting > worse. Has anybody used the above meidcaion. Will it work eventually? > I have been on this medicaiton now more than one month. Please help.

Hopefully it should work after a couple of weeks.  Most people find dothiepin to be quite sedating, but is can have a more activating effect in a few.  I’d give it about six weeks, to be honest, and if there’s still no luck I’d move onto something else.  I found both clomipramine and mirtazapine extremely sedating, considerably moreso than dothiepin whose effect tended to wear off a couple of weeks after each dose increase. Chris.

Response:

I am on 3 75 mcg dothiepin and 1 10 mcg zolpidem for depression. My depression has resulted in not being able to sleep nearly 3 months. The above medication is supposed to help me. I seem to be getting worse. Has anybody used the above meidcaion. Will it work eventually? I have been on this medicaiton now more than one month. Please help. Emrom

Response:

> I am on 3 75 mcg dothiepin and 1 10 mcg zolpidem for depression. My > depression has resulted in not being able to sleep nearly 3 months. > The above medication is supposed to help me. I seem to be getting > worse. Has anybody used the above meidcaion. Will it work eventually? > I have been on this medicaiton now more than one month. Please help.

I’ve taken dothiepin for chronic back pain.  It wasn’t combined with any other depression medication, but I was taking propranalol as a migraine preventative, rizatriptan when I had a migraine attack, anti-inflammatories and analgesics at the same time.  The dothiepin, quite simply, sedated me so much that I could hardly keep awake.  It has a known sedative effect, as does amitryptilene, which affected me in the same way.  Both took around a month to start affecting me in this way. I couldn’t take either of them because I wasn’t safe to drive and couldn’t operate at work properly.  That’s when my doctor suggested I try fluoxetine (Prozac), which has been wonderful for me because it works on my pain but doesn’t sedate me.  Certainly dothiepin should have some sort of sedative effect on you. Jamie

Response:

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