clomipramine: first dose- too sedated; sexual dysfunction

Question:

I tried my first dose of clomipramine-25mg, and I don’t like it. The side effect- extreme drowsiness, and impairment of my cognitive abilities- which I think comes from the drowsiness. I find that I can’t follow conversations- but this is from the drowsiness. As the morning progresses, I am a little clearer. Does the drowsiness abate after getting used to the med? After four days, I am supposed to take 50mg. Anyone experience sexual dysfunction with clomipramine? I am currently taking 45mg of Remeron which doesn’t interfere with sexual functioning. Keshet

Response:

I took clomipramine years and years ago (50 mg. daily). It is a very effective anti-depressant, and is also very helpful if you have any Obsessive-Compulsive tendencies. I eventually switched to Prozac because my work involves a lot of detail, both physically and mentally, and the brain fog and shakiness were unacceptable. If you are too "out of it" talk to your doctor. Perhaps you can either split up the dose or take it in the early evening when you are home for the night, or advise him that you find the side effects to overwhelming. Tricyclics are very good antidepressants, but they do carry more side effects than some other (SSRI) anti-depressants such as Prozac. Good luck. regards, Compucat  >^+^<

– Hide quoted text — Show quoted text -> I tried my first dose of clomipramine-25mg, and I don’t like it. The > side effect- extreme drowsiness, and impairment of my cognitive > abilities- which I think comes from the drowsiness. > I find that I can’t follow conversations- but this is from the > drowsiness. As the morning progresses, I am a little clearer. > Does the drowsiness abate after getting used to the med? After four > days, I am supposed to take 50mg. > Anyone experience sexual dysfunction with clomipramine? > I am currently taking 45mg of Remeron which doesn’t interfere with > sexual functioning. > Keshet

Response:

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